Comments on DNA synthesis in light of our deal with Twist

Ginkgo has just announced a commitment to buy 100 million base pairs of DNA from Twist Bioscience in 2016. By volume, this equals 10% of the global volume for gene synthesis in 2015. Here, I provide some context for how we, the customer, view an agreement like this. Engineering biology has become a big deal […]

A New Cultured Palette

“It’s sort of juicy…fruity?” “I’m getting melon and…caramel…?” “It’s just like peachy penguins!” We’re in Ginkgo’s foundry, Bioworks1, attempting to describe the smell of lactones, a family of scents that have a varied character, adding a creamy richness to everything from jasmine flowers to peach gummy candy to luxury perfume. Their smell is difficult to […]

The latency of gene synthesis – 2013 update

It’s been a while so I thought it was about time to do an updated post on observed turn times for commercial gene synthesis.  After all, Rob Carlson posted updated cost and productivity curves for DNA sequencing and synthesis.  As in my original post on this topic, I plot turn time vs length for orders […]

The lag phase of commercial gene synthesis

From synthetic biology’s earliest days, DNA synthesis, and more specifically gene synthesis, has been touted as the central, enabling technology of the field.  Gene synthesis is part of what lets us make the leap from the ad hoc, cut and paste of genetic engineering to the systematic design that is [or will be] the hallmark […]

Cambridge city council hearings on recombinant DNA technology

Jason Bobe pointed out on the DIYbio mailing list that video is now available online from the 1976 Cambridge, MA city council hearings on recombinant DNA technology. MIT Tech TV I saw this video a few years ago on VHS and was fascinated by the obvious parallels by the debates then on recombinant DNA and […]

Ginkgo organism engineers and the pipe

In a previous post, I discussed different platforms for organism engineering that were presented at SB5.0. Here I’ll try to give a high-level picture of Ginkgo’s pipeline for organism engineering. If you’ve checked out our webpage, you’ll see that we have several different organism engineering projects happening at Ginkgo that span several different hosts. Our […]

Emerging platforms for organism engineering

Synthetic biology 5.0 wrapped up a couple weeks ago and attending the conference reinforced for me that the field has developed sufficiently over the past few years that we are now seeing different platforms and/or schools of thought in how to engineer organisms start to coalesce. Chris Voigt gave a nice talk about how his […]

And the award goes to …

Our Ginkgo video “Who are the bioengineers of the future?” won the Online Audience Award at the Bio:Fiction Science, Art and Film Festival in Vienna. Congrats Christina and Patrick!

From the Ginkgo archives

For your consideration … brought to you by our friends at Hydrocalypse Industries.

Pilgrimage to Taq polymerase’s roots

Our friend Pete Carr who’s at MIT’s Media Lab came by for a visit last week. Apparently, Pete used to work for Cetus and through his connections there managed to figure out exactly where in Yellowstone National Park is Mushroom Pool, the location where Thomas Brock first discovered Thermus aquaticus in 1966. The thermophile Thermus […]